(Hemoglobin is a protein thats found in red blood cells.). And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. They can recommend appropriate treatment options. Venofer is not for treating other forms of anemia not caused by iron deficiency. If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. And this person had gotten their first dose of the drug without having an allergic reaction. Check with your pharmacist if you have questions about the best way to throw out drugs. I actually was constipated after my 3rd but didn't think anything of it. But keep in mind that in this study, delayed allergic reaction only occurred in one person. Should I avoid certain foods while taking Venofer Vial? Tell your doctor right away if you have any serious side effects, including: abdominal pain, chest pain, irregular heartbeat (arrhythmias), pressure in the chest, severe headache and blurred vision (hypertension), problems with your dialysis access site (graft). This includes people who: Usually, hypophosphatemia doesnt cause symptoms. All rights reserved. WebMD does not provide medical advice, diagnosis or treatment. Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. However, to be safe, tell your doctor or pharmacist about all prescription, over-the-counter, and other drugs you take before taking Injectafer. Available for Android and iOS devices. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. Boxed warnings alert doctors and patients about drug effects that may be dangerous. <> FG Trade/E+ sia Getty Images Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. Your doctor will go over your Venofer may reduce the absorption of iron preparations taken by mouth. If a person does not have an allergic response or any other unanticipated reactions, a doctor will administer the remaining iron. Or your doctor may recommend that you change your eating habits to include more iron in your diet. Data on file, American Regent, Inc. 1. Headache. Selected from data included with permission and copyrighted by First Databank, Inc. Allergic reactions are most likely to occur within 30 minutes of receiving Venofer. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Without enough hemoglobin, the right amount of oxygen may not reach certain parts of your body. And this can affect how well those parts of your body are able to work. The infusion will take between 15-30 minutes if it is given in. Drug class: Iron products. Notify your healthcare provider of any irritation at the injection site. MNT is the registered trade mark of Healthline Media. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. Its given by either intravenous (IV) infusion or slow IV injection. People with IDA have low blood levels of hemoglobin. (One treatment course includes two doses of the drug.) Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Here are answers to some frequently asked questions about Injectafer. Venofer is for use in adults and children at least 2 years old. Dizziness. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Hemoglobin is a protein thats found inside your red blood cells. Injectafer isnt available in a generic form. Others last much longer (even a lifetime), which can be quite traumatizing to people. <> Innovators Monograph Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. Canada residents can call a provincial poison control center. Administer Venofer in 3 divided doses, given by slow intravenous infusion, within a 28 day period: 2 infusions each of 300 mg over 1.5 hours 14 days apart followed by one 400 mg infusion over 2.5 hours 14 days later. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Pain in your limbs. For example: Say you weigh 105 pounds (about 48 kilograms). The information provided is not intended to replace your healthcare provider's medical advice. But for other people, their anemia may come back after Injectafer treatment. With this condition, you also have a low hemoglobin level. Here we look at how Injectafer and Feraheme are alike and different. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. A lack of iron can lead to iron deficiency anaemia if left untreated. In the US - Call your doctor for medical advice about side effects. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. For people weighing 50 kg (about 110 lb) or more, administer Injectafer in two doses of 750 mg, at least 7 days apart. Together, you and your doctor can discuss the benefits and risks of treatment options for anemia. Terminal half-life ranges from 7 to 12 hours. And babies born to those who took Injectafer during pregnancy didnt have any major congenital anomalies (also sometimes called birth defects). If youre interested in finding an alternative to Injectafer, talk with your doctor. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Low iron saturation, or iron deficiency, has various possible causes. stream An example of a drug interaction that many people are not aware of isgrapefruitjuice and statins. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Its not known if Injectafer is safe to use during pregnancy. Ask your doctor or healthcare provider if Venofer is the right choice for you. He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. ByDr. They can tell you about other medications that may work well for you. Injectafer can cause low blood levels of phosphorus, which is a condition called hypophosphatemia. To help make sure that you dont miss an appointment for your Injectafer dose, try setting an appointment reminder on your phone. Many patients with kidney disease cannot get enough iron from food and require injections. If you have questions about using Injectafer in a child, talk with your doctor. treatment schedule in further detail. Venofer may cause significant hypotension (decreased blood pressure). Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] This survey is being conducted by the WebMD marketing sciences department. But you dont necessarily need to eat these foods unless your doctor tells you to do so. Its possible to get rid of or reduce the severity ofside effects. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. Venofer Side Effects. All rights reserved. Answer by DrLact: About Venofer usage in lactation. The following information describes dosages that are commonly used or recommended. Your doctor will do laboratory tests to monitor your response. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Sharing this information can help you avoid potential interactions. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. The oral form of the drug, called sucroferric oxyhydroxide and used . Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when Venofer is injected. Patients with iron-deficiency anemia who are having high blood loss surgery (> 500 ml) within the next 2 months and need to replace iron quickly. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Can poor sleep impact your weight loss goals? These are not all the side effects that may occur; contact your healthcare provider if you have questions. Version: 7.01. (IV iron is absorbed by the body more rapidly than oral iron.) 5 0 obj Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. The following information is provided for clinicians and other healthcare professionals. Hypophosphatemia seems to mostly occur in people who are already at risk for low phosphorus levels. Together, they can recommend ways to help you manage a body weight thats healthy for you. There are currently no generic forms of either drug. }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Injectafer contains the active drug ferric carboxymaltose. If you have questions about side effects, call your doctor. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Keep all drugs out of the reach of children and pets. Call your doctor for instructions if you miss an appointment for your Venofer injection. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Before approving coverage for Injectafer, your insurance company may require you to get prior authorization. Do not flush down a toilet or pour down a drain unless you are told to do so. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. This site is intended for use only by US patients. endobj You may also report side effects at https://www.fda.gov/medwatch. Not all possible drug interactions are listed here. pain in the arms or legs. Brand-name medications usually cost more than generics. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. Many people using this medication do not have serious side effects.Severe dizziness or fainting (hypotension) may occur while you are receiving IV iron. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Examples of these side effects include dizziness and nausea. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. (A class of medications describes a group of drugs that work in the same way.). In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. endobj Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. Following an LSD trip, users may experience a sort of 'comedown.'. Do not share your drugs with others and do not take anyone else's drugs. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. If you notice other effects not listed above, contact your doctor or pharmacist. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. Someside effectsare temporary or last as long as the person continues takingprescription medicine. On day three I had a headache and felt heavy/exhausted, which lasted a few days.
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